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Developmental patterning relies on morphogen gradients, which generally involve feedback loops to buffer against perturbations caused by fluctuations in gene dosage and expression1.
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Morphogen - Wikipedia, the free encyclopedia
A morphogen is a substance governing the pattern of tissue development and, in particular, the positions of the various specialized cell types within a tissue. It spreads from a localized source and f...
en.wikipedia.org/wiki/Morphogen |
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Definition and other additional information on Morphogen from Biology-Online.org dictionary.
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A morphogen gradient is an important concept in developmental biology, because it describes a mechanism by which the emission of a signal from one part of an embryo can determine the location, differentiation and fate of many surrounding cells. ReviewGenetics of morphogen gradients. [Nat Rev Genet. 2001]
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morphogen. The American Heritage® Dictionary of the English Language: Fourth Edition. 2000.
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Morphogen summary with 3 pages of encyclopedia entries, research information, and more. A morphogen is a substance governing the pattern of tissue development and, in particular, the positions of the various specialized cell types within a tissue.
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In biology or chemistry, a morphogen is a chemical substance that effects the process of morphogenesis. For example, a typical morphogen in plants is a growth hormone. If the concentration of this growth hormone exceeds a certain threshold, cell division occurs.
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Hepatocyte Nuclear Factor 4 Provokes Expression of Epithelial Marker Genes, Acting As a Morphogen in Dedifferentiated Hepatoma Cells...
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The methods, compositions and devices on this invention all provide a therapeutically effective morphogen concentration to the hepatic cells to be treated.
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