serum sickness

noun Pathology.
a generalized allergic reaction to a foreign serum or drug, characterized by fever, skin rash, enlarged lymph nodes, and painful joints.
Also called serum disease.


Origin:
1910–15

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Collins
World English Dictionary
serum sickness
 
n
an allergic reaction, such as vomiting, skin rash, etc, that sometimes follows 2-3 weeks after an injection of a foreign serum

Collins English Dictionary - Complete & Unabridged 10th Edition
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American Heritage
Medical Dictionary

serum sickness n.
A hypersensitive reaction to the administration of a foreign serum, marked by fever, swelling, skin rash, and lymph node enlargement. Also called serum disease, serum reaction.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Encyclopedia Britannica
Encyclopedia

serum sickness

an allergic reaction to animal serum or antiserum injected into an individual's blood to provide immunity against such illnesses as tetanus, botulism, and snake-venom poisoning. Symptoms include skin eruption, itching, swelling of the face and extremities, fever, joint pain and sometimes swelling, abdominal pain, nausea, and vomiting; severe cases may also show neurological symptoms.

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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Example sentences
Serum sickness is a delayed type of drug allergy that occurs a week or more after exposure to a medication or vaccine.
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