[spahy-ruh-noh-lak-tohn, spahy-roh-, -ron-uh-]
noun Pharmacology.
a steroid, C 2 4 H 3 2 O 4 S, used in combination with other drugs as a diuretic and antihypertensive.

1955–60; alteration of spirolactone; see spiro-2, lactone

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World English Dictionary
spironolactone (ˌspaɪrənəʊˈlæktəʊn)
a diuretic that increases water loss from the kidneys and is much used to treat oedema in heart and kidney failure
[C20: from spiro-² + linking syllable -no- + lactone]

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Example sentences
Drugs that can increase aldosterone measurements include lithium, spironolactone, and verapamil.
Another drug, spironolactone, can prevent salt retention and help patients with severe heart failure.
Anti-androgen medications such as spironolactone may be tried if birth control pills do not work.
The drug, called spironolactone, was developed as a diuretic but was found to also clear up acne and facial hair.
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