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spironolactone

[spahy-ruh-noh-lak-tohn, spahy-roh-, -ron-uh-] /ˌspaɪ rə noʊˈlæk toʊn, spaɪˌroʊ-, -ˌrɒn ə-/
noun, Pharmacology
1.
a steroid, C 2 4 H 3 2 O 4 S, used in combination with other drugs as a diuretic and antihypertensive.
Origin
1955-1960
1955-60; alteration of spirolactone; see spiro-2, lactone
Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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Examples from the web for spironolactone
  • Drugs that can increase aldosterone measurements include lithium, spironolactone, and verapamil.
  • Another drug, spironolactone, can prevent salt retention and help patients with severe heart failure.
  • Anti-androgen medications such as spironolactone may be tried if birth control pills do not work.
  • The drug, called spironolactone, was developed as a diuretic but was found to also clear up acne and facial hair.
British Dictionary definitions for spironolactone

spironolactone

/ˌspaɪrənəʊˈlæktəʊn/
noun
1.
a diuretic that increases water loss from the kidneys and is much used to treat oedema in heart and kidney failure
Word Origin
C20: from spiro-² + linking syllable -no- + lactone
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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