"You canker blossom!" 3 Shakespearean Insults
1540s, from Latin designare "mark out, devise, choose, designate, appoint," from de- "out" (see de-) + signare "to mark," from signum "a mark, sign" (see sign (n.)). Originally in English with the meaning now attached to designate; many modern uses of design are metaphoric extensions. Related: Designed; designing.
1580s, from Middle French desseign "purpose, project, design," from Italian disegno, from disegnare "to mark out," from Latin designare "to mark out" (see design (v.)).