noun, plural maladies.
any disorder or disease of the body, especially one that is chronic or deepseated.
any undesirable or disordered condition: social maladies; a malady of the spirit.

1200–50; Middle English maladie < Old French, equivalent to malade sick (< Late Latin male habitus literally, ill-conditioned; see mal-, habit) + -ie -y3

malady, melody.

1. illness, sickness, affliction, complaint, ailment, indisposition. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
malady (ˈmælədɪ)
n , pl -dies
1.  any disease or illness
2.  any unhealthy, morbid, or desperate condition: a malady of the spirit
[C13: from Old French, from Vulgar Latin male habitus (unattested) in poor condition, from Latin male badly + habitus, from habēre to have]

Collins English Dictionary - Complete & Unabridged 10th Edition
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Word Origin & History

mid-13c., from O.Fr. maladie "sickness, illness, disease," from malade "ill," from L. male habitus "doing poorly, feeling sick," lit. "ill-conditioned," from male "badly" (see mal-) + habitus, pp. of habere "have, hold" (see habit). Related: Maladies.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

malady mal·a·dy (māl'ə-dē)
A disease, disorder, or ailment.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
Incidents of special needs are growing, and putting up a special building for
  each malady is not possible for most institutions.
Government statistics say about 4.4 million report having the malady in a given
Kidney stones are usually an adult malady, one that is notorious for causing
  excruciating pain — pain worse than childbirth.
This malady is, of course, stage fright.
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