a suffix found in French loanwords of Latin origin, usually diminutives, and later in adaptations of words borrowed directly from Latin or in Neo-Latin coinages: areole; centriole; vacuole.

< French < Latin -olus, -ola, -olum, variant of -ulus -ule with stems ending in a vowel

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a suffix used in names of chemical compounds, especially five-membered, unsaturated rings (carbazole; indole; thiazole ) and, less systematically, aromatic ethers (anisole; safrole ).
Also, -ol2.

< French < Latin oleum oil

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World English Dictionary
-ole or -ol1
n combining form
1.  denoting an organic unsaturated compound containing a 5-membered ring: thiazole
2.  denoting an aromatic organic ether: anisole
[from Latin oleum oil, from Greek elaion, from elaia olive]
-ol or -ol1
n combining form
[from Latin oleum oil, from Greek elaion, from elaia olive]

indicating something small: arteriole
[from Latin -olus, diminutive suffix]

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American Heritage
Medical Dictionary

-ole or -ol

  1. A usually heterocyclic chemical compound containing a five-membered ring: pyrrole.

  2. A chemical compound, especially an ether, that does not contain hydroxyl: indole.

The American Heritage® Stedman's Medical Dictionary
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