a suffix occurring in nouns that denote actions, conditions, or states (hypnosis; leukocytosis; osmosis ), especially disorders or abnormal states (chlorosis; neurofibromatosis; tuberculosis ).
Compare -otic.

on the model of Greek borrowings ending in Greek -ōsis, as sklērōsis sclerosis, derived orig. from verbs ending in the formative -o- (-ō- in noun derivatives), with the suffix -sis -sis

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World English Dictionary
suffix forming nouns
1.  indicating a process or state: metamorphosis
2.  Compare -iasis indicating a diseased condition: tuberculosis
3.  indicating the formation or development of something: fibrosis
[from Greek, suffix used to form nouns from verbs with infinitives in -oein or -oun]

Collins English Dictionary - Complete & Unabridged 10th Edition
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Word Origin & History

suffix expressing state or condition, in medical terminology denoting "a state of disease," from L. -osis, from Gk. -osis, formed from the aorist of verbs ending in -o. It corresponds to L. -atio.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

-osis suff.

  1. Condition; process; action: osmosis.

  2. Diseased or abnormal condition: neurosis.

  3. Increase; formation: leukocytosis.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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American Heritage
Science Dictionary
  1. A suffix that means:

  2. Diseased condition, as in tuberculosis.

  3. Condition or process, as in osmosis.

The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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