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-some1

1.
a native English suffix formerly used in the formation of adjectives:
quarrelsome; burdensome.
Origin
Middle English; Old English -sum; akin to Gothic -sama, German -sam; see same

-some2

1.
a collective suffix used with numerals:
twosome; threesome.
Origin
Middle English -sum, Old English sum; special use of some (pronoun)

-some3

1.
a combining form meaning “body,” used in the formation of compound words:
chromosome.
Also, -soma.
Origin
< Greek sôma body; see soma1
Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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British Dictionary definitions for -some

-some1

suffix
1.
characterized by; tending to awesome, tiresome
Word Origin
Old English -sum; related to Gothic -sama, German -sam

-some2

suffix
1.
indicating a group of a specified number of members threesome
Word Origin
Old English sum, special use of some (determiner)

-some3

/-səʊm/
combining form
1.
a body chromosome
Word Origin
from Greek sōma body
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for -some
-some
as a suffix forming adjectives, it represents O.E. -sum (see some; cf. O.Fris. -sum, Ger. -sam, O.N. -samr), related to sama "same." As a suffix added to numerals meaning "a group of that number" (cf. twosome) it represents O.E. sum "some," used after the genitive plural (cf. sixa sum "six-some"), the inflection disappearing in M.E. Use of some with a number meaning "approximately" also was in O.E.
Online Etymology Dictionary, © 2010 Douglas Harper
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-some in Medicine

-some suff.

  1. Body: centrosome.

  2. Chromosome: autosome.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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