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-ule

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-ule

a suffix occurring in loanwords from Latin, originally diminutive nouns (capsule; globule; nodule) or noun derivatives of verbs (ligule).

Origin:
< F < L -ulus, -ula, -ulum dim. formative with nouns of the 1st and 2d declensions ≪ *-el- (cf. -cle 1 , -elle, -ole 1 ); the deverbal suffix -ulus, etc. (cf. cingulum, tumulus ) is of distinct orig.
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Based on the Random House Dictionary, © Random House, Inc. 2009.
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-ule  
suff.  Small one: valvule.

[French, from Latin -ulus, -ula, -ulum, diminutive suff.]
The American Heritage® Dictionary of the English Language, Fourth Edition
Copyright © 2009 by Houghton Mifflin Company.
Published by Houghton Mifflin Company. All rights reserved.
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Word Origin & History

-ule 
suffix meaning "small, little" (capsule, module, etc.), from Fr. -ule, from L. diminutive suffix -ulus (fem. -ula, neut. -ulum).
Online Etymology Dictionary, © 2001 Douglas Harper
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