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Encyclopedia: Cysteine protease Source:Wikipedia
Proteases
are
enzymes
that degrade
polypeptides
.
Cysteine proteases
have a common catalytic mechanism that involves a
nucleophilic
cysteine
thiol
in a
catalytic triad
. The first step is deprotonation of a thiol in the enzyme's active site by an adjacent
amino acid
with a basic
...
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Cysteine Proteases |
The catalytic activity of the cystein proteases is indeed based on a nucleophilic attack of the cysteine residue, leading to a tetrahedral intermediate and then an acyl enzyme, just as in the serine ...
chemistry.umeche.maine.edu/CHY431/Peptidase10.html
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Identification of a Novel Maturation Mechanism and Restricted ... |
Identification of a Novel Maturation Mechanism and Restricted Substrate Specificity for the SspB Cysteine Protease of Staphylococcus aureus*
www.jbc.org/cgi/lookup?vol=277&fp=41770&view=abstract
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99k - 14 sec @ 56k
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Lysosomal Trafficking and Cysteine Protease Metabolism Confer ... |
Lysosomal Trafficking and Cysteine Protease Metabolism Confer Target-specific Cytotoxicity by Peptide-linked Anti-CD30-Auristatin Conjugates* ... Cysteine protease inhibitors, ...
www.jbc.org/cgi/content/abstract/281/15/10540
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Staphylococcus aureus-Derived Staphopain B, a Potent Cysteine ... |
Staphylococcus aureus-Derived Staphopain B, a Potent Cysteine Protease Activator of Plasma Chemerin1...
www.jimmunol.org/cgi/content/abstract/178/6/3713
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Cysteine protease B of Leishmania mexicana inhibits host Th1 ... |
Cysteine protease B of Leishmania mexicana inhibits host Th1 responses and protective immunity.
www.medscape.com/medline/abstract/14500670
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Purification and characterization of cysteine protease from ... |
Cysteine protease activity in mycelial culture increased 7. ... Purification and characterization of cysteine protease from Pleurotus ostreatus.
www.medscape.com/medline/abstract/9720226
Proteases are enzymes that degrade polypeptides. Cysteine proteases have a common catalytic mechanism that involves a nucleophilic cysteine thiol in a catalytic triad. The first step is deprotonation of a thiol in the enzyme's active site by an adjacent amino acid with a basic side chain, usually...
en.wikipedia.org/wiki/Cysteine_protease
en.wikipedia.org/wiki/Cysteine_protease
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New Treatment For Schistosomiasis (Bilharzia) |
A significant reduction in parasite burden and pathology by a vinyl sulfone cysteine protease inhibitor suggests a new direction for chemotherapy of human schistosomiasis.Citation: Abdul...
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Plasmodium falciparum cysteine protease falcipain-1 is not essential ... |
Plasmodium falciparum cysteine protease falcipain-1 is not essential in erythrocytic stage malaria parasites ... Cysteine protease inhibitors block hemoglobin hydrolysis and development by trophozoites, ...
www.pnas.org/cgi/content/full/101/23/8721
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The Plasmodium falciparum cysteine protease falcipain-2 captures its ... |
BIOCHEMISTRY The Plasmodium falciparum cysteine protease falcipain-2 captures its substrate, hemoglobin, via a unique motif
www.pnas.org/cgi/content/abstract/102/26/9138