done, operated, worked, etc., by the hand or hands rather than by an electrical or electronic device: a manual gearshift.
involving or using human effort, skill, power, energy, etc.; physical: manual labor.
of or pertaining to the hand or hands: manual deformities.
of the nature of a manual or handbook: manual instructions.
a small book, especially one giving information or instructions: a manual of mathematical tables.
a nonelectric or nonelectronic typewriter; a typewriter whose keys and carriage may be powered solely by the typist's hands.
Military. the prescribed drill in handling a rifle: the manual of arms.
Music. a keyboard, especially one of several belonging to a pipe organ.
Automotive. manual transmission.

1375–1425; < Latin manuālis (adj.), manuāle (noun) (something) that can be held in the hand (manu(s) hand + -ālis, -āle -al1, -al2); replacing late Middle English manuel < Middle French < Latin, as above

manually, adverb
nonmanual, adjective
nonmanually, adverb
unmanual, adjective
unmanually, adverb Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
manual (ˈmænjʊəl)
1.  of or relating to a hand or hands
2.  operated or done by hand: manual controls
3.  physical, as opposed to mental or mechanical: manual labour
4.  by human labour rather than automatic or computer-aided means
5.  of, relating to, or resembling a manual
6.  a book, esp of instructions or information: a car manual
7.  music one of the keyboards played by hand on an organ
8.  military the prescribed drill with small arms
[C15: via Old French from Latin manuālis, from manus hand]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

c.1400, from L. manualis "of or belonging to the hand," from manus "hand, strength, power over, armed force, handwriting," from PIE *men- "hand, to take in one's hand" (cf. O.E. mund "hand, protection, guardian," Ger. Vormund "guardian," Gk. mane "hand"). Related: Manually.

early 15c., "service book used by a priest," from O.Fr. manuel, from L.L. manuale "case or cover of a book, handbook," neut. of L. manualis (see manual (adj.)). Meaning "a concise handbook" of any sort is from 1530s.
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
Which is why his book is styled as a manual, full of sensible, practiced advice.
The antibody itself is not a vaccine, but it could be an instruction manual for
  making one.
To make the replacement, read the instruction manual to get an overview of the
One section of the manual covered the ejection system.
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