negate

[ni-geyt, neg-eyt]
verb (used with object), negated, negating.
1.
to deny the existence, evidence, or truth of: an investigation tending to negate any supernatural influences.
2.
to nullify or cause to be ineffective: Progress on the study has been negated by the lack of funds.
verb (used without object), negated, negating.
3.
to be negative; bring or cause negative results: a pessimism that always negates.

Origin:
1615–25; < Latin negātus (past participle of negāre to deny, refuse), equivalent to neg- (variant of nec not; see neglect) + -ā- theme vowel + -tus past participle suffix

negator, negater, noun
renegate, verb (used with object), renegated, renegating.
self-negating, adjective
unnegated, adjective
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Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
negate (nɪˈɡeɪt)
 
vb
1.  to make ineffective or void; nullify; invalidate
2.  to deny or contradict
 
[C17: from Latin negāre, from neg-, variant of nec not + aio I say]
 
ne'gator
 
n
 
ne'gater
 
n

Collins English Dictionary - Complete & Unabridged 10th Edition
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Word Origin & History

negate
1837, back formation from negation. Related: Negated; negates; negating.
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
And that negates some of the advantage of their initial cheapness.
Not that that necessarily negates anything, but the omission of a link to the
  source research doesn't help with credibility.
The tendency seems to be in dyslexia research that every new fact that is shown
  somehow negates all of the previous research.
The one-page enclosure of the same date negates that argument.
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