[n., adj. oh-pee-it, -eyt; v. oh-pee-eyt]
a drug containing opium or its derivatives, used in medicine for inducing sleep and relieving pain.
any sedative, soporific, or narcotic.
anything that causes dullness or inaction or that soothes the feelings.
mixed or prepared with opium.
inducing sleep; soporific; narcotic.
causing dullness or inaction.
verb (used with object), opiated, opiating.
to subject to an opiate; stupefy.
to dull or deaden.

1535–45; < Medieval Latin opiātus bringing sleep, equivalent to Latin opi(um) opium + -ātus -ate1

unopiated, adjective

2. drug. 3. anodyne. 5. sedative.

2. stimulant.
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Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
1.  any of various narcotic drugs, such as morphine and heroin, that act on opioid receptors
2.  any other narcotic or sedative drug
3.  something that soothes, deadens, or induces sleep
4.  containing or consisting of opium
5.  inducing relaxation; soporific
6.  to treat with an opiate
7.  to dull or deaden
[C16: from Medieval Latin opiātus; from Latin opium poppy juice, opium]

Collins English Dictionary - Complete & Unabridged 10th Edition
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Word Origin & History

1540s (adj.) "made with or containing opium," from M.L. opiatus, from L. opium (see opium). The noun is attested from c.1600; fig. sense of "anything that dulls the feelings" is from 1640s.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

opiate o·pi·ate (ō'pē-ĭt, -āt')

  1. Any of various sedative narcotics that contain opium or one or more of its natural or synthetic derivatives.

  2. A drug, hormone, or other chemical substance that has sedative or narcotic effects similar to those containing opium or its derivatives. Also called opioid.

  1. Of or containing opium or any of its derivatives.

  2. Resembling opium or its derivatives in activity.

  3. Inducing sleep or sedation; soporific.

v. o·pi·at·ed, o·pi·at·ing, o·pi·ates (-āt')
To subject to the action of an opiate.
o'pi·ate (-ĭt, -āt') adj.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
They were dedicated to the overthrow of religion and religious opiates.
For example, doctors have found that patients made to feel anxious need larger
  amounts of opiates after surgery than other people.
When a heroin user shoots up, the opiates in the drug plug into the nerve
  receptors normally occupied by endorphins.
Once morphine can be grown in vats, opiates will be even more impossible to
  control than today.
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