noun Informal.

1825–35, Americanism; shortened form; compare Dutch zus for zuster sister Unabridged


a suffix appearing in loanwords from Greek, where it was used to form from verbs abstract nouns of action, process, state, condition, etc.: thesis; aphesis.

< Greek Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
sis1 (sɪs)
informal short for sister

sis or sies2 (sɪs, siːs, sɪs, siːs)
informal (South African) an exclamation of disgust
[Afrikaans, possibly from Khoi]
sies or sies2
[Afrikaans, possibly from Khoi]

abbreviation for
1.  Also called: MI6 (in Britain) Secret Intelligence Service
2.  (in New Zealand) Security Intelligence Service

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

1656, abbreviated form of sister; in Amer.Eng., applied generally to girls and young women (1859).

suffix in Gk. nouns denoting action, process, state, condition, from Gk. -sis, which is identical in meaning with L. -entia, Eng. -ing.
Online Etymology Dictionary, © 2010 Douglas Harper
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Slang Dictionary

sis definition

  1. n.
    sister. (Also a term of address and a common pet name for one's sister.) : Come on, sis. We're going to be late.
Dictionary of American Slang and Colloquial Expressions by Richard A. Spears.Fourth Edition.
Copyright 2007. Published by McGraw-Hill Education.
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American Heritage
Abbreviations & Acronyms
National Library of Medicine [Specialized Information Services]
The American Heritage® Abbreviations Dictionary, Third Edition
Copyright © 2005 by Houghton Mifflin Company.
Published by Houghton Mifflin Company. All rights reserved.
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