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1520s, originally a sailors' word, from Middle Dutch splissen "to splice," ultimately from PIE *(s)plei- "to split, splice" (see flint). The Dutch word was borrowed in French as épisser. Used of motion picture film from 1912; of DNA from 1975. Related: Spliced; splicing.
To join together genes or gene fragments or insert them into a cell or other structure, such as a virus, by means of enzymes. In genetic engineering, scientists splice together genetic material to produce new genes or to alter a genetic structure. In messenger RNA, the introns are removed, and exons are spliced together to yield the final messenger RNA that is translated. See also exon, intron.
To marry • Most often in the passive: crying to be spliced (1751+)
permanent joining of two ropes by interweaving their strands. In the short splice the strands of each rope are unlayed (untwisted), interwoven, and tucked into the lay (twist) of the other rope. For neatness the strands are usually trimmed down before the final tuck is made.