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Old English sicol, probably a West Germanic borrowing (cf. Middle Dutch sickele, Dutch sikkel, Old High German sihhila, German Sichel) from Vulgar Latin *sicila, from Latin secula "sickle" (cf. Italian segolo "hatchet"), from PIE root *sek- "to cut" (see section (n.)). Applied to curved or crescent-shaped things from mid-15c. Sickle-cell anemia is first recorded 1922.
sickle sick·le (sĭk'əl)
v. sick·led, sick·ling, sick·les
To cut with a sickle.
To deform a red blood cell into an abnormal crescent shape.
To assume an abnormal crescent shape. Used of red blood cells.
of the Egyptians resembled that in modern use. The ears of corn were cut with it near the top of the straw. There was also a sickle used for warlike purposes, more correctly, however, called a pruning-hook (Deut. 16:9; Jer. 50:16, marg., "scythe;" Joel 3:13; Mark 4:29).