Medical Dictionary

acantholysis ac·an·thol·y·sis (āk'ān-thŏl'ĭ-sĭs, āk'ən-)
n. pl. ac·an·thol·y·ses (-sēz')
Separation of individual prickle cells from their neighbors, as in keratosis follicularis.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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a breakdown of a cell layer in the epidermis (as in pemphigus) 
WordNet® 3.0, © 2006 by Princeton University.
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