alkaline phosphatase

alkaline phosphatase

noun Biochemistry.
a phosphatase active in an alkaline medium.

Origin:
1945–50

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American Heritage
Medical Dictionary

alkaline phosphatase n.
A phosphatase with an optimum functioning at pH 8.6; it is present throughout the body.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Encyclopedia Britannica
Encyclopedia

alkaline phosphatase

enzyme that is normally present in high concentrations in growing bone and in bile. It is essential for the deposition of minerals in the bones and teeth. Alkaline phosphatase deficiency is a hereditary trait called hypophosphatasia, which results in bone deformities. In severe cases, the deficiency leads to early death from infection. Alkaline phosphatase is also present in the blood and is an important clinical diagnostic indicator for several illnesses, including chronic myelogenous leukemia.

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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