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1630s, back-formation from amputation or else from Latin amputatus, past participle of amputare "to cut off, to prune." Related: Amputated; amputating.
amputate am·pu·tate (ām'pyu-tāt')v. am·pu·tat·ed, am·pu·tat·ing, am·pu·tates To cut off a part of the body, especially by surgery.