Gangrene is not curable by current medical intervention once past a certain point in its progression, except by amputation.
In some cases, Roth said, amputation is the only solution to “fixing” horrible infections or deformities.
I will almost surely have to give it up: It is an amputation I may not be able to bear.
1610s, "a cutting off of tree branches, a pruning," also "operation of cutting off a limb, etc., of a body," from Middle French amputation or directly from Latin amputationem (nominative amputatio), noun of action from past participle stem of amputare "cut off, lop off; cut around, to prune," from am(bi)- "about" (see ambi-) + putare "to prune, trim" (see pave).
amputation am·pu·ta·tion (ām'pyu-tā'shən)
Surgical removal of all or part of a limb, an organ, or projecting part or process of the body.
Traumatic or spontaneous loss of a limb, organ, or part.
amputate am·pu·tate (ām'pyu-tāt')
v. am·pu·tat·ed, am·pu·tat·ing, am·pu·tates
To cut off a part of the body, especially by surgery.