a naturally occurring protein that inhibits endothelial proliferation and interferes with the growth of new blood vessels, investigated for use as an anticancer drug.
an·gi·o·stat·in (ān'jē-ō-stāt'n) n. A naturally occurring protein that is a specific inhibitor of endothelial proliferation and a potent angiogenesis inhibitor. It is under investigation as a potential cancer therapy.