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city, capital of Bolivar estado (state), southeastern Venezuela. It lies on a small hill on the south bank of the Orinoco River, opposite Soledad on the north. Its elevation ranges from 85 to 246 feet (26 to 75 m) above sea level; the average annual temperature is 85 F (29 C). The town was founded in 1764 as San Tomas de la Nueva Guayana de la Angostura. In 1846 the name was changed to honour the Venezuelan liberator Simon Bolivar. The bark of a local tree contributed to the flavour and medicinal qualities of Angostura Bitters, invented by Bolivar's Prussian physician in 1824. The bitters were manufactured in Ciudad Bolivar until 1875, when, owing to political instability in Venezuela, the company moved to Port of Spain, Trinidad