a medicine that relieves or allays pain.
anything that relieves distress or pain: The music was an anodyne to his grief.
relieving pain.
soothing to the mind or feelings.

1535–45; < Latin anōdynus < Greek anṓdynos painless, equivalent to an- an-1 + ōdyn- (stem of odýnē pain, with lengthening of o) + -os adj. suffix

anodynic [an-uh-din-ik] , adjective Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
anodyne (ˈænəˌdaɪn)
1.  a drug that relieves pain; analgesic
2.  anything that alleviates mental distress
3.  capable of relieving pain or distress
[C16: from Latin anōdynus, from Greek anōdunos painless, from an- + odunē pain]

Collins English Dictionary - Complete & Unabridged 10th Edition
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Word Origin & History

1540s, from M.L. anodynus "pain-removing," from L. anodynus "painless," from Gk. anodynos "free from pain," from an- "without" + odyne "pain," a word perhaps from PIE root *ed- "to eat" (cf., from the same root, Lith. edioti "to devour, bite," ediotis "to suffer pain"). In old slang, frequently a euphemism
for "death;" e.g. anodyne necklace "hangman's noose."
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

anodyne an·o·dyne (ān'ə-dīn')
An agent that relieves pain.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
In fact, some would consider it pedestrian, even anodyne.
Most politicians' blogs tend to degenerate into anodyne travelogues.
But for such a prodigy, his conducting style is sedate, almost anodyne.
It made anodyne pleas to both sides to refrain from using force.
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