of or pertaining to a gene that is derived from RNA or complementary DNA, is inserted in reverse orientation into a strand of DNA, and is used in genetic engineering to regulate genetic expression of a trait.
antisense an·ti·sense (ān'tē-sěns', ān'tī-) adj. Of, relating to, or being nucleotide sequences that mimic DNA sequences but cannot serve as a template for mRNA, thus serving to disrupt genetic replication.
(ān'tē-sěns', ān'tī-) Relating to a nucleotide sequence that is complementary to a sequence of messenger RNA. When antisense DNA or RNA is added to a cell, it binds to a specific messenger RNA molecule and inactivates it.