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[an-ti-his-tuh-meen, -min] /ˌæn tɪˈhɪs təˌmin, -mɪn/
noun, Physiology, Pharmacology
any of certain compounds or medicines that neutralize or inhibit the effect of histamine in the body, used chiefly in the treatment of allergic disorders and colds.
Origin of antihistamine
1930-35; anti- + histamine Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2015.
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Examples from the web for antihistamine
  • Both experts recommended trying an over-the-counter antihistamine.
  • Parents sometimes consider giving infants an antihistamine when traveling to help them sleep on the flights.
  • Also, pack some antihistamine to use in an emergency if someone in your family has an allergic reaction while you are traveling.
  • Other drugs combine two varieties of the same ingredient, such as the allergy-reliever antihistamine.
  • Users say the antihistamine is good for preventing rash, but it's mostly to increase the volume of a shot.
  • Dimenhydrinate is a type of medicine called an antihistamine.
  • Hydroxyzine is an antihistamine used to treat symptoms of allergies and motion sickness.
  • In some cases, decongestants or a nasal spray containing an antihistamine may help.
  • Caused by an allergic reaction-- consult your doctor about antihistamine or steroid treatment.
  • Such drugs typically also include a diuretic to reduce fluid and an antihistamine.
British Dictionary definitions for antihistamine


/ˌæntɪˈhɪstəˌmiːn; -mɪn/
any drug that neutralizes the effects of histamine, used esp in the treatment of allergies
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for antihistamine

1933, from anti- + histamine.

Online Etymology Dictionary, © 2010 Douglas Harper
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antihistamine in Medicine

antihistamine an·ti·his·ta·mine (ān'tē-hĭs'tə-mēn', -mĭn)
Any of several drugs used to counteract the physiological effects of histamine.

an'ti·his'ta·mine' adj.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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antihistamine in Science
Any of various drugs that relieve cold or allergy symptoms by blocking the action of histamine.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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