|1.||the superlative of good|
|2.||most excellent of a particular group, category, etc|
|3.||most suitable, advantageous, desirable, attractive, etc|
|4.||the best part of most of: the best part of an hour|
|5.||put one's best foot forward|
|a. to do one's utmost to make progress|
|b. to hurry|
|6.||the superlative of well|
|7.||in a manner surpassing all others; most excellently, advantageously, attractively, etc|
|8.||(in combination) in or to the greatest degree or extent; most: the best-loved hero|
|9.||as best one can, as best one may as effectively as possible within one's limitations|
|10.||had best would be wise, sensible, etc, to: you had best go now|
|11.||the best the most outstanding or excellent person, thing, or group in a category|
|13.||the most effective effort of which a person or group is capable: even their best was inadequate|
|14.||a winning majority: the best of three games|
|15.||Also: all the best best wishes: she sent him her best|
|16.||a person's smartest outfit of clothing|
|a. in the most favourable interpretation|
|b. under the most favourable conditions|
|18.||for the best|
|a. for an ultimately good outcome|
|b. with good intentions: he meant it for the best|
|19.||get the best of, have the best of to surpass, defeat, or outwit; better|
|20.||give someone the best to concede someone's superiority|
|21.||make the best of to cope as well as possible in the unfavourable circumstances of (often in the phrases make the best of a bad job, make the best of it)|
|22.||informal six of the best six strokes with a cane on the buttocks or hand|
|23.||(tr) to gain the advantage over or defeat|
|[Old English betst; related to Gothic batista, Old High German bezzist]|
Best (běst), Charles Herbert. 1899-1978.
American-born Canadian physiologist noted for the discovery and successful clinical application of insulin.
|Best (běst) Pronunciation Key
American-born Canadian physiologist who assisted Frederick Banting in the discovery of the hormone insulin. In acknowledgment of his work, Banting shared his portion of the 1923 Nobel Prize with Best. In addition to further refining the use of insulin, Best later discovered the vitamin choline and the enzyme histaminase, which breaks down histamine.
Under the most favorable circumstances, as in At best we'll be just one week behind schedule, or Cleaning out the attic is a tedious job at best. This idiom, formerly also put as at the best, today is most often used in situations that are actually far from ideal, as in the examples above. [First half of 1300s] For an antonym, see at worst.