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autoantibody au·to·an·ti·bod·y (ô'tō-ān'tĭ-bŏd'ē)
An antibody that attacks the cells and tissues of the organism in which it was formed.
harmful antibody that attacks components of the body called self antigens. Normally autoantibodies are routinely eliminated by the immune system's self-regulatory process-probably through the neutralization of autoantibody-producing lymphocytes before they mature. At times this process fails, and antibodies that react to self constituents proliferate.