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| the estimation of something as valueless (encountered mainly as an example of one of the longest words in the English language). |
| opposition to the withdrawal of state support or recognition from an established church, esp. the Anglican Church in 19th-century England. |
azathioprine az·a·thi·o·prine (āz'ə-thī'ə-prēn')
n.
An immunosuppressive agent used especially to prevent organ rejection in kidney transplant recipients.
azathioprine
immunosuppressive drug that is used to treat rheumatoid arthritis and to suppress the body's rejection of transplanted organs. By inhibiting several enzymatic pathways required for the synthesis of deoxyribonucleic acid (DNA), azathioprine decreases the number of lymphocytes (a type of white blood cell) that can migrate to inflammatory sites. Leukopenia (an abnormally low number of white blood cells in the circulation) is the major undesirable side effect of the drug, although anemia and hemorrhage may also occur. When used with allopurinol, the pharmacological effect of azathioprine is increased.
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