azathioprine

[az-uh-thahy-uh-preen]
noun Pharmacology.
a cytotoxic purine analog, C 9 H 7 N 7 O 2 S, used as an immunosuppressive in organ transplantations and in rheumatoid arthritis and connective tissue disorders.

Origin:
1960–65; coinage apparently based on imidazol, thio-, and purine, parts of the chemical name

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World English Dictionary
azathioprine (ˌæzəˈθaɪəˌpriːn)
 
n
a synthetic drug that suppresses the normal immune responses of the body and is administered orally during and after organ transplantation and also in certain types of autoimmune disease. Formula: C9H7N7O2S
 
[C20: from aza- + thio- + p(u)rine]

Collins English Dictionary - Complete & Unabridged 10th Edition
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American Heritage
Medical Dictionary

azathioprine az·a·thi·o·prine (āz'ə-thī'ə-prēn')
n.
An immunosuppressive agent used especially to prevent organ rejection in kidney transplant recipients.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Encyclopedia Britannica
Encyclopedia

azathioprine

immunosuppressive drug that is used to treat rheumatoid arthritis and to suppress the body's rejection of transplanted organs. By inhibiting several enzymatic pathways required for the synthesis of deoxyribonucleic acid (DNA), azathioprine decreases the number of lymphocytes (a type of white blood cell) that can migrate to inflammatory sites. Leukopenia (an abnormally low number of white blood cells in the circulation) is the major undesirable side effect of the drug, although anemia and hemorrhage may also occur. When used with allopurinol, the pharmacological effect of azathioprine is increased.

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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Example sentences
Allopurinol interacts with certain other drugs, such as azathioprine.
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