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A spherical object or mass.
A large pill or bolus.
[1880s+; probably fr the helplessness of a horse on a slippery street when its shoes have accumulated balls of ice; somehow the term has come to be associated with the testicles, as the related term bollixed up shows]
ball up, beanball, butterfly ball, cannonball, carry the load, fireball, forkball, foul ball, get on the ball, go for the long ball, goofball, gopher ball, greaseball, greedball, have a ball, junk-ball, keep one's eye on the ball, meatball, not get one's balls in an uproar, nutball, oddball, on the ball, play ball, play catch-up, sleazebag, slimebag, softball, sourball, that's the way the ball bounces