"You canker blossom!" 3 Shakespearean Insults
1718, apparently from East Anglian dialectic bunny "lump, swelling" (16c.), which is probably from Middle French buigne "bump on the head, swelling from a blow" (see bun).
bunion bun·ion (bŭn'yən)n. A localized swelling at either the medial or dorsal aspect of the first joint of the big toe, caused by an inflamed bursa.