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"bad general state of health," 1540s, from Latinized form of Greek kakhexia "bad habits," from kakos "bad" (see caco-) + -exia, related to exis "habit or state," from exein "to have, be in a condition," from PIE root *segh- "to hold, hold in one's power, to have" (see scheme (n.)). Related: cachexic.
cachexia ca·chex·i·a (kə-kěk'sē-ə)
Weight loss, wasting of muscle, loss of appetite, and general debility that can occur during a chronic disease.