with certainty; without doubt; assuredly: I'll certainly be there.
yes, of course: Certainly, take the keys.
surely; to be sure: He certainly is successful.

1250–1300; Middle English; see certain, -ly

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certainly (ˈsɜːtənlɪ)
1.  with certainty; without doubt: he certainly rides very well
sentence substitute
2.  by all means; definitely: used in answer to questions

Collins English Dictionary - Complete & Unabridged 10th Edition
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Word Origin & History

c.1300, in all main modern senses, from certain (q.v.).
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
Hill's status as a labor icon and the debate about his conviction certainly
  never died.
If that was ever true, it is certainly not so now in our scientific era.
But some of our ancestors were almost certainly food for other primates.
It's certainly no replacement for a proper doctor, but as a technological
  demonstration, it's surprisingly impressive.
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