noun Pathology.
the initial lesion of syphilis and certain other infectious diseases, commonly a more or less distinct ulcer or sore with a hard base.

1595–1605; < Middle FrenchLatin cancrum, accusative of cancer cancer

chancrous, adjective Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
chancre (ˈʃæŋkə)
pathol a small hard nodular growth, which is the first diagnostic sign of acquired syphilis
[C16: from French, from Latin: cancer]

Collins English Dictionary - Complete & Unabridged 10th Edition
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Word Origin & History

c.1605, "venereal ulcer," from Fr. chancre, lit. "cancer," from L. cancer (see cancer).
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

chancre chan·cre (shāng'kər)
The primary lesion of syphilis; a hard, nonsensitive, dull red papule or area of infiltration that begins at the site of infection after an interval of 10 to 30 days. Also called hard chancre, hard ulcer.

chan'crous (-krəs) adj.
The American Heritage® Stedman's Medical Dictionary
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