Smith (smĭth), Hamilton Othanel. Born 1931.
American microbiologist. He shared a 1978 Nobel Prize for the discovery of restriction enzymes and their application to molecular genetics.
|Smith (smĭth) Pronunciation Key
American microbiologist who isolated bacterial enzymes that could split genetic DNA into fragments large enough to retain genetic information but small enough to permit chemical analysis. The existence of these compounds (called restriction enzymes) was earlier predicted by Werner Arber, and their discovery revolutionized genetic engineering. For this work Smith shared the 1978 Nobel Prize for physiology or medicine with Arber and Daniel Nathans.
|Smith, , Michael 1932-2000.
British-born Canadian biochemist who developed a method for making a specific genetic mutation at any spot on a DNA molecule. He shared with American biochemist Kary B. Mullis the 1993 Nobel Prize for chemistry.