noun Biochemistry.
an amino acid, NH 2 CONH(CH 2 ) 3 CHNH 2 COOH, abundant in watermelons and an intermediate compound in the urea cycle.

1930; < Neo-Latin citrull(us) the watermelon genus (Medieval Latin citrul(l)us, citrolus, Latinization of South Italian citrulo, Tuscan citri(u)olo < Late Latin citrium watermelon (derivative of Latincitrus (see citrus); apparently in reference to the citroncolored fruit of some types of watermelon), with -uolo < Latin -eolus) + -ine2 Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
citrulline (ˈsɪtrəˌliːn)
an amino acid that occurs in watermelons and is an intermediate in the formation of urea. Formula: NH2CONH(CH2)3CHNH2COOH
[C20: from Medieval Latin citrullus a kind of watermelon, from Latin citron, referring to its colour]

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American Heritage
Medical Dictionary

citrulline cit·rul·line (sĭt'rə-lēn')
An amino acid produced as an intermediate in the conversion of ornithine to arginine during urea formation in the liver.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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American Heritage
Science Dictionary
citrulline   (sĭt'rə-lēn')  Pronunciation Key 
An amino acid originally isolated from watermelon, occurring mostly in the liver as an intermediate in the conversion of ornithine to arginine during urea formation. Chemical formula: C6H13N3O3.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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Example sentences
Citrulline is an amino acid first isolated from watermelon juice.
Citrulline has potential antioxidant and vasodilatation roles.
To determine the level of citrulline to produce a given amount of arginine in healthy volunteers and surgical patients.
Nitric oxide is made from other common compounds arginine and citrulline that are normally found in our bodies.
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