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cleidocranial dysostosis

cleidocranial dysostosis in Medicine

cleidocranial dysostosis or clidocranial dysostosis
A congenital complex that may be hereditary and is characterized by absent or rudimentary development of the clavicles, an enlarged incompletely ossified skull with frontal protuberances, and poor tooth formation. Also called cleidocranial dysplasia, craniocleidodysostosis.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Encyclopedia Article for cleidocranial dysostosis

rare congenital, hereditary disorder characterized by collarbones that are absent or reduced in size, skull abnormalities, and abnormal dentition. The shoulders may sometimes touch in front of the chest, and certain facial bones are underdeveloped or missing. Cranial sutures are late in fusing, and the skull is round and the eyes are set wide apart. Other bones, especially the radius (in the forearm), pelvis, hip joint, and vertebrae, may be malformed. Deciduous teeth are late in falling out, and, as a result, the permanent teeth are often abnormal. Individuals are not disabled beyond difficulty in walking, and life expectancy is normal.

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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