|1.||a soft thick lump or mass: a clot of blood|
|2.||informal (Brit) a stupid person; fool|
|—vb , clots, clotting, clotted|
|3.||to form or cause to form into a soft thick lump or lumps|
|[Old English clott, of Germanic origin; compare Middle Dutch klotte block, lump]|
A soft, nonrigid, insoluble mass formed when blood or lymph gels. v. clot·ted, clot·ting, clots
|clot (klŏt) Pronunciation Key
A soft insoluble mass formed when blood or lymph gels. During blood clotting, white blood cells, red blood cells, platelets, and various clotting factors interact in a cascade of chemical reactions initiated by a wound. When a body tissue is injured, calcium ions and platelets act on prothrombin to produce the enzyme thrombin. Thrombin then catalyzes the conversion of the protein fibrinogen into fibrin, a fibrous protein that holds the clot together. An abnormal clot inside the blood vessels or the heart (a thrombus or an embolus) can obstruct blood flow.