| 1. | Biochemistry. any of various organic or inorganic substances necessary to the function of an enzyme. |
| 2. | Mathematics.
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cofactor co·fac·tor (kō'fāk'tər)
n.
A substance, such as a metallic iron or coenzyme, that must be associated with an enzyme for the substance to function.
| cofactor (kō'fāk'tər) Pronunciation Key
A substance, such as a metallic ion or a coenzyme, that must be associated with an enzyme for the enzyme to function. Cofactors work by changing the shape of an enzyme or by actually participating in the enzymatic reaction. |