The salicylate of colchicine is stable in water and may be given in doses of about one-thirtieth of a grain.
It is, therefore, evident that there are in man no constant pathological changes from colchicine poisoning.
When that is done, colchicine may be found to exhibit a definite chemical interaction with this hitherto undiscovered substance.
It is much stronger than the common extract, and contains the acetate of colchicine.
This year we have treated a number of seedlings with colchicine.
colchicine is the active principle and may be given in full form in doses of 1⁄32 to 1⁄16 grain.
The chief constituents of colchicum are two alkaloids, colchicine and veratrine.
Casper puts the lethal dose of colchicine at from 25 to 30 mgrms.