[kol-chuh-seen, -sin, kol-kuh-]
noun Pharmacology.
a pale yellow, crystalline alkaloid, C 22 H 25 NO 6 , the active principle of colchicum.

1850–55; colchic(um) + -ine2 Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
colchicine (ˈkɒltʃɪˌsiːn, -sɪn, ˈkɒlkɪ-)
a pale-yellow crystalline alkaloid extracted from seeds or corms of the autumn crocus. It is used in the treatment of gout and to create polyploid plants by inhibiting chromosome separation during meiosis. Formula: C22H25NO6
[C19: from colchicum + -ine²]

Collins English Dictionary - Complete & Unabridged 10th Edition
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Encyclopedia Britannica


drug used in the treatment of gout, a disease that is characterized by severe inflammation in one or more of the joints of the extremities. Colchicine is obtained from the autumn crocus (Colchicum autumnale). The mechanism by which colchicine relieves the pain of gout, which is caused by solid deposits of uric acid in the joints, the kidneys, and other tissues, is unknown. Side effects include diarrhea and other gastrointestinal disturbances.

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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Example sentences
Colchicine may be taken by mouth or given by an intravenous line.
Colchicine also interacts with several other medications.
Colchicine can be added to prevent further acute attacks.
Colchicine, a drug used for gout, can cause urge incontinence.
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