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colchicine

[kol-chuh-seen, -sin, kol-kuh-] /ˈkɒl tʃəˌsin, -sɪn, ˈkɒl kə-/
noun, Pharmacology
1.
a pale yellow, crystalline alkaloid, C 22 H 25 NO 6 , the active principle of colchicum.
Origin
1850-1855
1850-55; colchic(um) + -ine2
Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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Examples from the web for colchicine
  • colchicine may be taken by mouth or given by an intravenous line.
  • colchicine also interacts with several other medications.
  • colchicine can be added to prevent further acute attacks.
  • colchicine, a drug used for gout, can cause urge incontinence.
  • Treatment with colchicine of triploid triticale gives fertile hexaploid triticale.
British Dictionary definitions for colchicine

colchicine

/ˈkɒltʃɪˌsiːn; -sɪn; ˈkɒlkɪ-/
noun
1.
a pale-yellow crystalline alkaloid extracted from seeds or corms of the autumn crocus. It is used in the treatment of gout and to create polyploid plants by inhibiting chromosome separation during meiosis. Formula: C22H25NO6
Word Origin
C19: from colchicum + -ine²
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Encyclopedia Article for colchicine

drug used in the treatment of gout, a disease that is characterized by severe inflammation in one or more of the joints of the extremities. Colchicine is obtained from the autumn crocus (Colchicum autumnale). The mechanism by which colchicine relieves the pain of gout, which is caused by solid deposits of uric acid in the joints, the kidneys, and other tissues, is unknown. Side effects include diarrhea and other gastrointestinal disturbances.

Learn more about colchicine with a free trial on Britannica.com
Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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