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complementfixation test

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com⋅ple⋅ment-fix⋅a⋅tion test

[kom-pluh-muhnt-fik-sey-shuhn]
–noun Medicine/Medical.
a test for diagnosing an infectious disease by detecting the presence of antibody in the blood, based on the fixing of a known quantity of complement to the antigen being tested and the specific antibody that combines with it. Abbreviation: CFT

Origin:
1910–15
Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2009.
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Medical Dictionary

Main Entry: complement–fixation test
Function: noun
: a diagnostic test for the presence of a particular antibody in the serum of a patient that involvesinactivation of the complement in the serum, addition of measured amounts of the antigen for which the antibody is specific and of foreign complement, and detection of the presence or absence ofcomplement fixation by the addition of a suitable indicator system —compare WASSERMANN TEST
Merriam-Webster's Medical Dictionary, © 2002 Merriam-Webster, Inc.
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Medical Dictionary

complement-fixation test n.
An immunological test for determining the presence of a particular antibody in which serum is treated in a manner that allows existing antibodies to accept and bind to a known amount of antigen. If binding occurs the presence of the antibody is verified and its concentration in the serum can be calculated based on the amount of antigen added to the system.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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