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constant region

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constant region  
n.  The portion of the carboxyl terminal of an immunoglobulin's heavy and light chains having an amino acid sequence that does not vary within a given class or subclass of immunoglobulin.
The American Heritage® Dictionary of the English Language, Fourth Edition
Copyright © 2009 by Houghton Mifflin Company.
Published by Houghton Mifflin Company. All rights reserved.
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Medical Dictionary

Main Entry: constant region
Function: noun
: the part of the polypeptide chain of a light or heavy chain of an antibody that ends in a free carboxyl group -COOH and thatis relatively constant in its sequence of amino acid residues from one antibody to another called also constant domain; —compare VARIABLE REGION
Merriam-Webster's Medical Dictionary, © 2002 Merriam-Webster, Inc.
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Science Dictionary
constant region  
The portion of the amino acid sequence of an antibody's heavy or light chains that determines the class of the antibody and does not vary within a given class. The constant region terminates in a free carboxyl group (COOH). Unlike the variable region, the constant region does not interact with antigens. Compare variable region.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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