cooleys anemia

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Cooley's anemia

–noun

Origin:
1930–35; named after Thomas Benton Cooley (1871–1945), U.S. pediatrician, who reported incidences of the disease

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thal⋅as⋅se⋅mi⋅a

[thal-uh-see-mee-uh]

–noun Pathology.

a hereditary form of anemia, occurring chiefly in people of Mediterranean origin, marked by the abnormal synthesis of hemoglobin and a consequent shortened life span of red blood cells.

Also called Cooley's anemia.

Origin:
1932; < Gk thálass(a) sea (alluding to the Mediterranean Sea; the anemia was first reported among children in Mediterranean countries) + -emia

Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2009.
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Link To cooleys anemia

Medical Dictionary

Main Entry: Coo·ley's anemia
Pronunciation: "kü-lEz-
Function: noun
: a severe thalassemic anemia that is associated with the presence ofmicrocytes, enlargement of the liver and spleen, increase in the erythroid bone marrow, and jaundice and that occurs especially in children of Mediterranean parents called also thalassemia major
Cooley /'kü-lE,/ Thomas Benton (1871–1945), American pediatrician. Cooley was one of the first modern pediatricians and a founder of the American Academyof Pediatrics. Interested in the etiology of childhood diseases, he focused his research on hematology and the anemias. His most important contribution was the identification of the familial anemiathat bears his name. In 1927 Cooley, E. R. Witwer, and O. P. Lee described this anemia, frequently called thalassemia, that at first was thought to occur only in children of Mediterranean stock.

Main Entry: thal·as·se·mia
Variant: or British thal·as·sae·mia /"thal-&-'sE-mE-&/
Function: noun
: any of a group of inherited hypochromic anemias and especially Cooley's anemia controlled by a series of allelic genes that cause reduction in or failure of synthesis of one of the globinchains making up hemoglobin and that tend to occur especially in individuals of Mediterranean, African, or southeastern Asian ancestry—sometimes used with a prefix (as alpha-, beta-, or delta-)to indicate the hemoglobin chain affected; called also Mediterranean anemia; —see BETA THALASSEMIA

Merriam-Webster's Medical Dictionary, © 2002 Merriam-Webster, Inc.
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Medical Dictionary

Cooley's anemia Coo·ley's anemia (k&oomacr;'lēz)
n.
See thalassemia major.

thalassemia thal·as·se·mi·a (thāl'ə-sē'mē-ə)
n.
Any of a group of inherited forms of anemia occurring chiefly among people of Mediterranean descent, caused by faulty synthesis of part of the hemoglobin molecule.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Science Dictionary

thalassemia (thāl'ə-sē'mē-ə) Pronunciation Key
Any of a group of inherited forms of anemia occurring chiefly among people of Mediterranean descent, caused by faulty synthesis of part of the hemoglobin molecule

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