cooperativity

cooperativity

[koh-op-er-uh-tiv-i-tee]
noun Biochemistry.
the increase or decrease in the rate of interaction between a reactant and a protein as the reactant concentration increases.
Also, co-operativity.


Origin:
cooperative + -ity

Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
Cite This Source Link To cooperativity
Collins
World English Dictionary
cooperativity (kəʊˌɒpərəˈtɪvɪtɪ)
 
n
biochem, chem an interaction between structural units within a molecule or between molecules in an assemblage that enables the system to respond more sharply to an external change than would isolated units

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
Cite This Source
Encyclopedia Britannica
Encyclopedia

cooperativity

in enzymology, a phenomenon in which the shape of one subunit of an enzyme consisting of several subunits is altered by the substrate (the substance upon which an enzyme acts to form a product) or some other molecule so as to change the shape of a neighbouring subunit. The result is that the binding of a second substrate molecule to the second subunit of the enzyme differs in strength or velocity from that of the first, the third from the second, and so on. If the change in shape of the first subunit makes easier the binding of substrate to the second subunit, the effect is called positive cooperativity. In negative cooperativity, the binding of a molecule to the first subunit makes more difficult the binding of substrate to the second. See also allosteric control.

Learn more about cooperativity with a free trial on Britannica.com.

Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
Cite This Source
Copyright © 2014 Dictionary.com, LLC. All rights reserved.
  • Please Login or Sign Up to use the Recent Searches feature