the resistance to one or more effects of a substance because of tolerance to a pharmacologically similar substance: a cross-tolerance of some alcoholics to anesthetics.
Main Entry: cross–tol·er·ance Pronunciation: 'kro-'stäl(-&)-r&n(t)s Function: noun : tolerance or resistance to a drug thatdevelops through continued use of another drug with similar pharmacological action
[kraws-tol-er-uh
ns, kros-] 