|1.||(intr) to lose heart or hope; become disheartened; despair|
|2.||archaic lack of hope; despondency|
|[C17: from Latin dēspondēre to promise, make over to, yield, lose heart, from |
|a calculus or concretion found in the stomach or intestines of certain animals, esp. ruminants, formerly reputed to be an effective remedy for poison.|
|a fool or simpleton; ninny.|
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