depopulate

[v. dee-pop-yuh-leyt; adj. dee-pop-yuh-lit, -leyt]
verb (used with object), depopulated, depopulating.
1.
to remove or reduce the population of, as by destruction or expulsion.
adjective
2.
Archaic. depopulated.

Origin:
1525–35; < Latin dēpopulātus devastated (past participle of dēpopulārī), equivalent to dē- de- + populātus; see populate

depopulation, noun
depopulative, adjective
depopulator, noun
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World English Dictionary
depopulate (dɪˈpɒpjʊˌleɪt)
 
vb
to be or cause to be reduced in population
 
depopu'lation
 
n

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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Etymonline
Word Origin & History

depopulate
1540s, from de- + populate.
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
Depopulate, consume less and plant lots and lots of trees.
And that's what makes it such an effective way to terrorize people and
  depopulate an area.
The decision was made to then depopulate the facility so it can be cleaned and
  decontaminated.
Four markets depopulate more frequently than the required monthly depopulation.
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