noun Slang.

probably euphemistic variant of diddlyshit

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World English Dictionary
diddly-squat (ˌdɪdlɪˈskwɒt)
informal (US), (Canadian) (usually used with a negative) anything: that doesn't mean diddly-squat

Collins English Dictionary - Complete & Unabridged 10th Edition
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Example sentences
The breakthroughs get a lot of attention, but attention means diddly-squat in the bigger picture.
It's because the university tests that have shown diddly-squat.
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