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Down syndrome
noun Pathology.
a genetic disorder, associated with the presence of an extra chromosome 21, characterized by mild to severe mental impairment, weak muscle tone, shorter stature, and a flattened facial profile.
Also, Down's syndrome.
Also called trisomy 21.
See trisomy.
Origin:
1960–65; after John L. H. Down (1828–96), British physician
1960–65; after John L. H. Down (1828–96), British physician
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Down syndrome
is always a great word to know.
So is flibbertigibbet. Does it mean:
| a chattering or flighty, light-headed person. |
| a scrap or morsel of food left at a meal. |
Dictionary.com Unabridged
Down's syndrome
Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2012.
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Based on the Random House Dictionary, © Random House, Inc. 2012.
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Link To down syndrome
Collins
World English Dictionary
| Down's syndrome or (US) Down syndrome | |
| —n | |
| a. pathol Former name: mongolism, Technical name: trisomy 21 a condition caused by the presence of an extra copy of chromosome 21 resulting in learning difficulties and physical differences, such as shorter stature | |
| b. (as modifier): a Down's syndrome baby | |
| usage | |
| Down syndrome or (US) Down syndrome | |
| —n | |
| usage | |
Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Etymonline
Word Origin & History
Down's Syndrome
1961, from J.L.H. Down (1828-1896), English physician; chosen as a less racist name for the condition than earlier mongolism.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary
Down syndrome (doun) or Down's syndrome (dounz)
n.
A congenital disorder, caused by the presence of an extra 21st chromosome, in which the affected person has mild to moderate mental retardation, short stature, and a flattened facial profile. Also called trisomy 21, trisomy 21 syndrome.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
Cite This Source
American Heritage
Science Dictionary
Down syndrome (doun) or Down's Syndrome  (doun) Pronunciation Key
A congenital disorder caused by the presence of an extra 21st chromosome. People with down syndrome have mild to moderate mental retardation, short stature, and a flattened facial profile. The syndrome is named after its discoverer, British physician John Langdon Haydon Down (1828-1896). |
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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American Heritage
Cultural Dictionary
Down's syndrome definition
A congenital condition, caused by an abnormality in the chromosomes, marked by moderate to severe mental retardation and changes in certain physical features.
The American Heritage® New Dictionary of Cultural Literacy, Third Edition
Copyright © 2005 by Houghton Mifflin Company.
Published by Houghton Mifflin Company. All rights reserved.
Cite This Source
Copyright © 2005 by Houghton Mifflin Company.
Published by Houghton Mifflin Company. All rights reserved.
Cite This Source
Word Dynamo Rating For Down syndrome
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