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Dubin Johnson syndrome Du·bin John·son syndrome (dōō'bĭn-jŏn'sən, dyōō'-)
An inherited defect in hepatic excretory function marked by an increase of serum bilirubin concentration, an excessive urinary excretion of abnormal proportions of a form of coproporphyrin, a retention of dark pigment by hepatocytes, and the nonvisualization of the gall bladder using a cholecystogram. Also called chronic idiopathic jaundice.