dyshematopoiesis dys·he·ma·to·poi·e·sis (dĭs-hē'mə-tō-poi-ē'sĭs, dĭs'hĭ-māt'ə-) or dys·he·mo·poi·e·sis (dĭs-hē'mə-) n. Abnormal formation of blood cells.